Assay
Age
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Immunohistochemistry (whole mount)
7.5 DPC
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Sox2 SRY (sex determining region Y)-box 2 (Synonyms: lcc, Sox-2, ysb) | |
Results | Reference |
1 | J:340418 Amadei G, Handford CE, Qiu C, De Jonghe J, Greenfeld H, Tran M, Martin BK, Chen DY, Aguilera-Castrejon A, Hanna JH, Elowitz MB, Hollfelder F, Shendure J, Glover DM, Zernicka-Goetz M, Embryo model completes gastrulation to neurulation and organogenesis. Nature. 2022 Oct;610(7930):143-153 |
1 | J:342647 Chakraborty S, Kopitchinski N, Zuo Z, Eraso A, Awasthi P, Chari R, Mitra A, Tobias IC, Moorthy SD, Dale RK, Mitchell JA, Petros TJ, Rocha PP, Enhancer-promoter interactions can bypass CTCF-mediated boundaries and contribute to phenotypic robustness. Nat Genet. 2023 Feb;55(2):280-290 |
1 | J:189004 Iwafuchi-Doi M, Matsuda K, Murakami K, Niwa H, Tesar PJ, Aruga J, Matsuo I, Kondoh H, Transcriptional regulatory networks in epiblast cells and during anterior neural plate development as modeled in epiblast stem cells. Development. 2012 Nov;139(21):3926-37 |
1* | J:278249 Iwafuchi-Doi M, Yoshida Y, Onichtchouk D, Leichsenring M, Driever W, Takemoto T, Uchikawa M, Kamachi Y, Kondoh H, The Pou5f1/Pou3f-dependent but SoxB-independent regulation of conserved enhancer N2 initiates Sox2 expression during epiblast to neural plate stages in vertebrates. Dev Biol. 2011 Apr 15;352(2):354-66 |
1 | J:137186 Kurimoto K, Yabuta Y, Ohinata Y, Shigeta M, Yamanaka K, Saitou M, Complex genome-wide transcription dynamics orchestrated by Blimp1 for the specification of the germ cell lineage in mice. Genes Dev. 2008 Jun 15;22(12):1617-35 |
1 | J:244157 Lange L, Marks M, Liu J, Wittler L, Bauer H, Piehl S, Blass G, Timmermann B, Herrmann BG, Patterning and gastrulation defects caused by the tw18 lethal are due to loss of Ppp2r1a. Biol Open. 2017 Jun 15;6(6):752-764 |
1 | J:308524 Morgani SM, Hadjantonakis AK, Quantitative analysis of signaling responses during mouse primordial germ cell specification. Biol Open. 2021 May 15;10(5):bio058741 |
1 | J:308051 Morgani SM, Su J, Nichols J, Massague J, Hadjantonakis AK, The transcription factor Rreb1 regulates epithelial architecture, invasiveness, and vasculogenesis in early mouse embryos. Elife. 2021 Apr 30;10:e64811 |
1 | J:324629 Nishio M, Matsuura T, Hibi S, Ohta S, Oka C, Sasai N, Ishida Y, Matsuda E, Heterozygous loss of Zbtb38 leads to early embryonic lethality via the suppression of Nanog and Sox2 expression. Cell Prolif. 2022 Apr;55(4):e13215 |
1 | J:334500 Ruthig VA, Yokonishi T, Friedersdorf MB, Batchvarova S, Hardy J, Garness JA, Keene JD, Capel B, A transgenic DND1GFP fusion allele reports in vivo expression and RNA-binding targets in undifferentiated mouse germ cells. Biol Reprod. 2021 Apr 1;104(4):861-874 |
1 | J:341534 Thawani A, Maunsell HR, Zhang H, Ankamreddy H, Groves AK, The Foxi3 transcription factor is necessary for the fate restriction of placodal lineages at the neural plate border. Development. 2023 Oct 1;150(19):dev202047 |
1* | J:233954 Tu S, Narendra V, Yamaji M, Vidal SE, Rojas LA, Wang X, Kim SY, Garcia BA, Tuschl T, Stadtfeld M, Reinberg D, Co-repressor CBFA2T2 regulates pluripotency and germline development. Nature. 2016 Jun 16;534(7607):387-90 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/07/2024 MGI 6.23 |
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